From episode 149 on the ECC Feed with Nick Merwood and Kasra Ahmadi.
Have you heard about using cholestyramine as a decontaminant for toxins that undergo enterohepatic recirculation? Here something important to know about cholestyramine for cases or anticoagulant rat baits ingestion/ toxicity:
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Cholestyramine would, in theory, work as a decontamination for most anticoagulant rodenticides. Potentially very useful news.
BUT
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It is also great at catching Vitamin K as it’s cycled between the liver and gut, and then holding it’s hand all the way out the poop hole, instead of into your patient’s clotting cascade.
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In other words, as you’re starting to experiment with cholestyramine in your toxin cases, don’t be tempted to give it to your rat bait patient that is already on Vit K, as it will reduce the amount of vitamin K being absorbed into the blood stream.
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